Effects of melatonin in reducing the toxic enects of doxorubicin

Oz E., Ilhan M. N.

MOLECULAR AND CELLULAR BIOCHEMISTRY, cilt.286, ss.11-15, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 286
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1007/s11010-005-9003-8
  • Dergi Adı: MOLECULAR AND CELLULAR BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.11-15
  • Anahtar Kelimeler: doxorubicin-induced toxicity, lipid peroxidation, melatonin, CONSTANT LIGHT EXPOSURE, HYPERLIPIDEMIC NEPHROPATHY, OXIDATIVE STRESS, LIPID-PEROXIDATION, RAT-BRAIN, ADRIAMYCIN, CARDIOTOXICITY, THERAPY, CANCER, DAMAGE
  • Gazi Üniversitesi Adresli: Evet

Özet

Anthracycline antibiotics, such as doxorubicin and daunorubicin, constitute a group of wide spectrum therapeutic agents. Application of these drugs in chemotherapy is limited because of their toxic effects. Melatonin, the main secretory product of pineal gland, was recently found as a free radical scavenger and antioxidant.